Dendritic Cells

Dendritic cells perform their daily tasks by acting as an antigen encloseing cell to efficiently introduce the antigen to separate immune cells locate in the body. The Dendritic cell activates when it detects a harmful strange substance in the body such as a bacteria, parasite, or viruses. Once the dendrite cell detects the strange substance it, it captures it and presents the antigen to the other immune cells located in the body. The interactions of dendritic cells differ depending on the locations in the body. Some of the most common origins where dendritic cells be present are: the skin, lymph nodes, and the spleen.
Dendritic cells are located in the skin and mucus passages, because a virus or foreign substance is most likely transmitted through these openings. The dendritic cells located on the skin are as well as know as the immature stage, because of their low population of molecules (CD80, CD86,CD83).The dendritic cells in the immature stage basically just lay well-nigh until the immune system is invaded. Once a virus or bacteria enter the dendritic cells immediately activate, but it is non mature enough to be able to respond. The skin overly does not require a mature enough phenotype. The dc cells that lack maturation to respond to the viral substance, penetrates into the openings of the body.



The skin dc cells are too immature to reach the t-cells, so in response it carries the antigen to mature part of the body known as the lymph nodes.
Once the cell reaches the lymph nodes, it no longer needs to present antigens to the rest of the immune system. The dendritic cells from the skin present a part of the antigen to the lymph node dendritic cells. Once this occurs, the lymph nodes detect which molecules to sour in order to fight off the bacteria. This stage is also known as the mature stage because it contains the molecules needed to stimulate the t- cell and the b-cell. Once the t-cell and b-cell are activated it turns on th1 and...If you ask to get a full essay, order it on our website: Ordercustompaper.com



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